This page explains what happens if Allopurinol and Aspirin are taken together, according to official sources.
Antagonism of uric acid reduction
Aspirin at low to moderate doses causes renal urate retention, opposing the therapeutic hypouricemic efficacy of allopurinol.
Monitor serum uric acid levels. In acute gout attacks, avoid aspirin for analgesia; utilize alternative prescribed agents.
Last updated: Sep 25, 2026
Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.