This page explains what happens if Allopurinol and Furosemide are taken together, according to official sources.
Diuretic-induced hyperuricemia opposing allopurinol
Furosemide promotes renal uric acid reabsorption, which can elevate serum urate and counteract the therapeutic goals of allopurinol.
Monitor serum uric acid levels. An upward titration of allopurinol may be required to maintain target urate levels (<6 mg/dL).
Last updated: Sep 25, 2026
Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.