MajorAzithromycin + Ciprofloxacin

Can you take Azithromycin and Ciprofloxacin together?

This page explains what happens if Azithromycin and Ciprofloxacin are taken together, according to official sources.

What happens

Severe risk of lethal QT prolongation and Torsades de Pointes

Co-prescribing azithromycin with ciprofloxacin causes additive prolongation of the cardiac QT interval, predisposing to fatal Torsades de Pointes.

Recommended management

Avoid concurrent administration. If alternative antimicrobials cannot be used, continuous cardiac telemetry and baseline QTc monitoring are mandatory.

Talk to your doctor or pharmacist about these two medicines; don't stop a prescribed medicine on your own.

Clinical references

Last updated: Sep 25, 2026

Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.