ModerateAzithromycin + Warfarin

Can you take Azithromycin and Warfarin together?

This page explains what happens if Azithromycin and Warfarin are taken together, according to official sources.

What happens

Potential elevated INR and bleeding risk

Azithromycin can enhance the effect of warfarin and elevate INR in some patients. Monitor INR during antibiotic therapy and for several days afterward, and watch for signs of bleeding.

Recommended management

Check INR when initiating or completing azithromycin therapy and monitor closely for unusual bleeding or bruising.

Clinical references

Last updated: Sep 25, 2026

Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.