ModerateCiprofloxacin + Diazepam

Can you take Ciprofloxacin and Diazepam together?

This page explains what happens if Ciprofloxacin and Diazepam are taken together, according to official sources.

What happens

Inhibition of diazepam clearance and enhanced sedation

Ciprofloxacin inhibits the hepatic clearance of diazepam, resulting in increased plasma concentrations, prolonged half-life, and marked sedation.

Recommended management

Advise patients of prolonged psychomotor impairment. Avoid driving or operating machinery; adjust benzodiazepine dose if needed.

Clinical references

Last updated: Sep 25, 2026

Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.