MajorCiprofloxacin + Warfarin

Can you take Ciprofloxacin and Warfarin together?

This page explains what happens if Ciprofloxacin and Warfarin are taken together, according to official sources.

What happens

Increased warfarin effect

Ciprofloxacin strengthens warfarin effect and elevates INR levels, increasing bleeding risk.

Recommended management

Recheck INR within 48-72 hours of antibiotic initiation. Warfarin dose reduction (typically 25-50%) is routinely required under physician guidance.

Talk to your doctor or pharmacist about these two medicines; don't stop a prescribed medicine on your own.

Clinical references

Last updated: Sep 25, 2026

Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.