MajorClopidogrel + Diclofenac

Can you take Clopidogrel and Diclofenac together?

This page explains what happens if Clopidogrel and Diclofenac are taken together, according to official sources.

What happens

Severe gastrointestinal bleeding risk

Diclofenac causes gastric mucosal ulceration while clopidogrel blocks platelet clotting, compounding severe gastrointestinal bleeding.

Recommended management

Avoid NSAIDs like diclofenac in patients on clopidogrel. Use paracetamol for analgesia and consult your doctor.

Talk to your doctor or pharmacist about these two medicines; don't stop a prescribed medicine on your own.

Clinical references

Last updated: Sep 25, 2026

Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.