MajorClopidogrel + Warfarin

Can you take Clopidogrel and Warfarin together?

This page explains what happens if Clopidogrel and Warfarin are taken together, according to official sources.

What happens

High risk of severe bleeding

Combining warfarin with clopidogrel synergistically increases the danger of major and life-threatening gastrointestinal or intracranial bleeding.

Recommended management

Use only when strictly indicated (e.g. post-coronary stenting with atrial fibrillation). Monitor INR frequently and evaluate for early bleeding signs.

Talk to your doctor or pharmacist about these two medicines; don't stop a prescribed medicine on your own.

Clinical references

Last updated: Sep 25, 2026

Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.