This page explains what happens if Diazepam and Metronidazole are taken together, according to official sources.
Metronidazole impairment of diazepam oxidation
Metronidazole can impair the oxidative hepatic breakdown of diazepam, potentiating central nervous system depression and somnolence.
Warn patients regarding augmented sedation and delayed reflexes. Exercise caution with ambulation in frail older adults.
Last updated: Sep 25, 2026
Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.