This page explains what happens if Diazepam and Omeprazole are taken together, according to official sources.
Increased sedation
Omeprazole can prolong diazepam clearance in the body and increase sedative effects.
Exercise caution with tasks requiring mental alertness (driving, machinery). Consider alternative gastroprotective agents with low enzyme inhibition (e.g. famotidine, pantoprazole).
Last updated: Sep 25, 2026
Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.