This page explains what happens if Diclofenac and Ibuprofen are taken together, according to official sources.
Dual NSAID toxicity: severe ulceration and renal damage
Combining two systemic NSAIDs provides no added analgesic benefit while exponentially raising the danger of peptic ulcer, GI bleeding, and acute renal failure.
Never combine two systemic NSAIDs simultaneously. Select a single agent at the lowest effective dose or switch to paracetamol.
Talk to your doctor or pharmacist about these two medicines; don't stop a prescribed medicine on your own.
Last updated: Sep 25, 2026
Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.