ModerateFurosemide + Levothyroxine

Can you take Furosemide and Levothyroxine together?

This page explains what happens if Furosemide and Levothyroxine are taken together, according to official sources.

What happens

Displacement of thyroxine from plasma proteins by high-dose furosemide

High doses of furosemide (>80 mg) competitively displace thyroxine from thyroid-binding globulin, transiently altering free thyroid hormone fractions.

Recommended management

Ensure routine Free T4 and TSH evaluation in patients receiving high-dose intravenous or oral loop diuretics.

Clinical references

Last updated: Sep 25, 2026

Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.