This page explains what happens if Ibuprofen and Lisinopril are taken together, according to official sources.
Reduced antihypertensive effect and renal risk
Ibuprofen can reduce the blood-pressure-lowering effect of lisinopril and place stress on the kidneys, especially in the elderly, during dehydration, or if furosemide is also taken. For short-term pain relief, paracetamol is safer. Consult a doctor before prolonged use.
Use paracetamol for short-term pain relief; monitor blood pressure and renal function during prolonged use.
Last updated: Sep 25, 2026
Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.