This page explains what happens if Metformin and Prednisone are taken together, according to official sources.
High blood sugar
Corticosteroids raise blood sugar and reduce metformin effect. Sugar must be checked more frequently.
Intensify daily self-monitoring of blood glucose. Temporary dosage escalation of antidiabetic therapy is frequently needed under medical guidance.
Last updated: Sep 25, 2026
Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.