This page explains what happens if Omeprazole and Prednisolone are taken together, according to official sources.
Beneficial gastroprotection against steroid ulceration
Omeprazole is routinely co-prescribed with prednisolone to prevent corticosteroid-induced gastritis and peptic ulceration.
Take omeprazole in the morning on an empty stomach. If steroid treatment is prolonged, evaluate calcium and bone density.
Last updated: Sep 25, 2026
Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.