This page explains what happens if Prednisolone and Warfarin are taken together, according to official sources.
Gastrointestinal bleeding and INR variability
Prednisolone weakens gastrointestinal mucosal integrity and can unpredictably alter INR, increasing internal bleeding risk.
Monitor INR closely when adding, titrating, or discontinuing prednisolone. Consider gastroprotective co-therapy with a PPI.
Last updated: Sep 25, 2026
Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.