This page explains what happens if Sertraline and Warfarin are taken together, according to official sources.
Increased bleeding vulnerability
Sertraline impairs platelet aggregation by depleting serotonin, synergizing with warfarin to elevate bleeding frequency.
Monitor closely for bruising or mucosal bleeding. Verify INR stabilization during sertraline titration.
Last updated: Sep 25, 2026
Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.