ModerateDiclofenac + Furosemide

Can you take Diclofenac and Furosemide together?

This page explains what happens if Diclofenac and Furosemide are taken together, according to official sources.

What happens

Blunted diuretic response and risk of azotemia

Diclofenac antagonizes furosemide natriuresis, worsening heart failure or edema and predisposing to prerenal azotemia.

Recommended management

Track daily weight and peripheral swelling. Minimize NSAID exposure and monitor renal function (BUN/creatinine).

Clinical references

Last updated: Sep 25, 2026

Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.