ModerateDiclofenac + Lisinopril

Can you take Diclofenac and Lisinopril together?

This page explains what happens if Diclofenac and Lisinopril are taken together, according to official sources.

What happens

Impaired renal function and reduced BP control

Diclofenac attenuates the antihypertensive action of lisinopril and substantially elevates the risk of acute renal dysfunction, especially in dehydrated patients.

Recommended management

Monitor blood pressure, serum creatinine, and potassium. Use paracetamol as the preferred analgesic for hypertensive patients on ACE inhibitors.

Clinical references

Last updated: Sep 25, 2026

Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.