ModerateFurosemide + Sertraline

Can you take Furosemide and Sertraline together?

This page explains what happens if Furosemide and Sertraline are taken together, according to official sources.

What happens

Enhanced hyponatremia risk in geriatric patients

SSRIs such as sertraline cause syndrome of inappropriate antidiuretic hormone secretion (SIADH); co-prescribing furosemide compounds hyponatremia risk.

Recommended management

Check baseline and follow-up electrolyte panels (sodium and potassium) within 2 weeks of initiation in older adults.

Clinical references

Last updated: Sep 25, 2026

Before changing or stopping any medicine, ask your doctor or pharmacist. Never stop your medicine on your own.